Studies on Anthelmintics. IV

Studies on Self-Sterility. IV. Selective Fertilization.

INTRODUCTION .................................................................. 346 Discussion of the problem ..................................................... 348 Pollen-tube frequency distributions ............................................. 349 Influence of growth of compatible pollen tubes upon incompatible pollen tubes.. .. 352 SUMMARY AND DISCUSSION ....................................

Structural studies on human type IV collagen.

Type IV collagen was isolated from limited pepsin digests of human placenta by selective salt precipitation at acidic and neutral pH. The native protein was resistant to human skin collagenase but was cleaved by a rat mast cell protease. Molecular sieve chromatography of the reduced and alkylated material separated relatively homogeneous components of molecular weight 140,000 (140K) and 100,000...

Studies on Plasma Protein. IV. Leprosy

Anthelmintics – From Discovery to Resistance

The scientific meeting entitled 'Anthelmintics: From Discovery to Resistance' was held in San Francisco in February 2014. The themes of the meeting were drug discovery, modes of action and resistance. Both human and veterinary parasites were covered in the oral and poster presentations. The attendees were from both academic and industrial backgrounds. In the present article we introduce a numbe...

Studies in enteric anthelmintics: activity profile of prodrug of a bisbenzimidazole [1].

The comparative anthelmintic activity of a possible prodrug, 2,2'-dicarbomethoxyamino-5,5'-dibenzimidazolyl methanol (2) with its parent compound 2,2'-dicarbomethoxyamino-5,5'-dibenzimidazolyl ketone (1) and the reference drug mebendazole (3a) is reported. At a dose of 25 mg/kg, compound 2 was 100% effective against Ancylostoma ceylanicum in hamsters. Compound 2 also exhibited a similar order o...